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In animal studies, GLP-1 agonists triggered anxiety early in treatment which then subsided and shifted toward reduced depression-like behaviour with continued use

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Tirzepatide (Mounjaro) vs semaglutide (Ozempic/Wegovy) 2026: 22% vs 15% weight loss, A1C -2.3% vs -1.8%, $1,069 vs $936 cost

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