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doi: 10.3389/fphar.2016.00433

Dietary bioactives derived from natural products have demonstrated significant promise in regulating metabolic pathways, including incretin secretion

Endocrine Effects of Soluble DPP4 on Cardiovascular Homeostasis Although it is well established that serum levels of sDPP4 are altered in several pathological conditions and that sDPP4 is released from vascular cells, only a minor part of research has focused on potential endocrine effects of this proteolytic enzyme

These changes are likely the result of weight loss and sagging skin, which can change the appearance of the genital area