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Your healthcare team will need to assess whether: Alternative glucose-lowering medications should be started before or immediately after stopping Rybelsus Your current diabetes regimen requires adjustment (e.g., increasing doses of metformin or other agents) More frequent blood glucose monitoring is needed during the transition period, including ketone testing if your glucose levels rise above 15 mmol/L or if you become unwell [11] [12] Lifestyle interventions require intensification to maintain glycaemic control In practice, many clinicians prefer a planned, supervised approach rather than abrupt cessation, not because tapering is pharmacologically necessary, but to ensure continuity of diabetes care and prevent metabolic decompensation

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NICE guidance also applies in Wales

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Small savings in other areas can make a treatment budget easier to maintain

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