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'This multi-strain probiotic is formulated with beneficial bacteria that naturally increase GLP-1, the un-hunger hormone that helps curb cravings and appetite,' per the Pendulum website

2.3 Role of taste receptors in the gastrointestinal hormone secretion Although, we commonly associate TRCs and TASR only to the oral cavity, they are also localized in extra-oral tissues, including the gastrointestinal tract, where they participate in energy homeostasis by modulating enteroendocrine hormone release (GLP-1, GIP, CCK, PYY) and nutrient sensing, thereby influencing gastric emptying and metabolic adjustments (e.g., glycemia) (15, 59, 60)

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Just last week, the agency issued a warning letter to Hims over advertising claims tied to compounded GLP-1s, a sign this issue is moving quickly into FDAs enforcement crosshairs