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Cell bodies of PPG neurons also have been described in the adjacent medullary reticular formation, both in rodents, non-human primates, and humans [21,22,23,24,25,26], as well as in a small population of glutamatergic olfactory bulb interneurons that express PPG that can modulate the firing pattern of the mitral cells in rodents [13,22,23,27,28]

Viana, The impact of glucagon-like peptide-1 receptor agonists (GLP-1 RA) on weight loss following bariatric treatment: a systematic review and meta-analysis

In contrast, underweight patients ( 100 kg group), although the number of cases was limited (507 cases), necessitating cautious interpretation

Another study conducted in 2022 (4) had similar results, once again showing Ozempic to be effective in losing weight, but once stopped, had no effect on weight maintenance