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Description
Once these fat cells become overfilled, they turn insulin resistant, meaning they stop accepting more energy (Bikman, 2020)

It represents a fundamental shift in how obesity should be treated in clinical practice

Its not necessary to wean off of semaglutide, but it still might be a good idea

Methods This is a cohort study combining several population-wide databases and covering a Spanish population of five million inhabitants, including all adults with obesity who initiated treatment with either GLP-1RA or SGLT-2i for type 2 diabetes from 2015 to 2021
