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Soluble epoxide hydrolase inhibition exerts beneficial anti-remodeling actions post-myocardial infarction

Statistical analysis was performed using IBM SPSS Statistics, version 27.0 (IBM Corporation, Armonk, New York, USA)

Hematoxylin and eosin (H&E) staining was used to assess overall tissue morphology and local tissue response, while Massons trichrome staining was used to evaluate fibrosis at the injection sites

This immunometabolic crosstalk provides a biologically plausible link between metabolic dysfunction and musculoskeletal inflammation, and supports the hypothesis that targeting incretin pathways could interfere with disease evolution at a preclinical or early PsA