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Over the past few decades, increasing prevalence of obesity caused an enormous medical, social, and economic burden

But another conversation has begun gaining momentum centered on fiber and the gut microbiome.
Depletion of luminal Na+ did not affect l-valine-induced GLP-1 secretion (P>0.05), suggesting that co-transport of l-valine and Na+ is not important for the depolarization necessary to activate the voltage-gated Ca2+-channels

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