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Description
Glycemic Control# Liraglutide (LEAD Program)# LEAD trials demonstrated HbA1c reductions of 1.0-1.5% at 1.2-1.8 mg daily Victoza approved for T2D at max 1.8 mg daily Effective monotherapy and combination therapy for glucose control Tirzepatide (SURPASS Program)# SURPASS-1 (monotherapy): HbA1c reduction of 2.07% at 15 mg over 40 weeks SURPASS-2 (vs semaglutide 1.0 mg): Superior HbA1c reduction (2.46% vs 1.86%) Up to 2.58% HbA1c reduction across SURPASS trials Tirzepatide's dual incretin mechanism provides markedly superior glycemic control, driven by additive insulin-sensitizing and insulinotropic effects from both receptor pathways
Planning ahead Many patients find it helpful to plan storage for different scenarios
Verly et al
Like any weight loss program, results are maintained by adopting long-term lifestyle changes
