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Description
Muscle loss or reduced muscle tone This isnt a direct effect of the medication, but losing weight quickly without enough protein or strength training can lead to muscle loss

In order to maintain the bile acid pool, therefore, the amount of bile acid excreted is almost equal to the amount newly synthesized by the liver
The study duration spanned 68 weeks, with most significant loss occurring during the first 16 weeks as the dose was gradually increased from starting levels

There were no clinically significant observations in clinical laboratory assessments, vital signs, physical examination, or electrocardiogram
