how to lose weight on glp 1 GLP-1 Loss Injections: Semaglutide and Tirzepatide Unlocking Sustainable Weight Loss with

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doi: 10.3389/fmed.2026.1763185 Received 08 December 2025 Revised 20 January 2026 Accepted 26 January 2026 Published 12 February 2026 Volume 13 - 2026 Edited by Jianbin Zhang, Dalian Medical University, China Reviewed by Theodoros Androutsakos, National and Kapodistrian University of Athens, Greece Feng Zhang, Nanjing University of Chinese Medicine, China Updates Copyright 2026 Lu and Yang

In addition to gastroparesis, other common gastrointestinal symptoms linked to tirzepatide include nausea, constipation, decreased appetite, indigestion (dyspepsia), diarrhea, and vomiting

(3) Notably, only 53.8% of those prescribed a GLP-1 agonist in 2022 had a history of type 2 diabetes, highlighting a shifting clinical paradigm in which these agents are now widely used for obesity management and related metabolic disorders