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The numbers from clinical data tell a compelling story
1 2 Diabetes & Metabolism
DPP-IV is an enzyme responsible for the degradation of incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP)
In contrast, long-acting agonists (such as albiglutide or dulaglutide, or extended-release exenetide) have a stronger effect to reduce fasting glucose levels mediated by their effect on insulin and glucagon release
