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These feelings can be exacerbated by weight gain or being unable to lose weight, which is a common concern among people with PCOS
Animal studies have suggested that metformin enhances the weight loss efficacy of GLP-1 RAs by stimulating GLP-1 receptor expression and augmenting insulin-mediated signaling pathways
Studies have shown significant reductions in body weight compared to placebo, with many participants achieving clinically meaningful results
