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While the weight loss is moderate compared to newer agents, the tolerability profile is genuinely superior for many individuals

The effect of oral semaglutide on cardiovascular outcomes was consistent with other clinical trials involving injectable semaglutide, but more trials are needed to determine if one method may be more effective than the other at reducing major cardiovascular events

HS-20094 has successfully completed multiple Phase II trials with positive efficacy and safety data and is currently being investigated in ongoing Phase III trial in China

doi: 10.1053/j.ajkd.2008.03.004
