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If youre thinking about GLP-1 injections in Norfolk, Nebraska, the most important step is that first conversation

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In the SURPASS trials, tirzepatide demonstrated superior A1C reduction and weight loss compared to semaglutide at equivalent dose levels

The presence of GLP-1R in the phylogenetically oldest parts of the brain but not in the cortex emphasizes that GLP-1 is involved in the regulation of vital functions like feeding and satiety (141)