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Description
NG101 is an oral, small molecule peripherally acting dopamine D2 receptor antagonist that has recently completed a proof-of-concept safety and efficacy study in nausea and vomiting associated with glucagon-like peptide 1 (GLP-1) agonists and a Ph2 trial in gastroparesis
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Pl: placebo
Previous studies show that obese mice lacking Klb expression in the forebrain (Camk2a Klb/ ) are resistant to the suppressive effects of recombinant FGF21 on body weight and energy expenditure [41]
