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They can review factors such as your personal and family health history, current weight, and health conditions to determine if GLP-1 therapy is suitable for you

In terms of lowering HbA1c, dulaglutide, when administered once a week, was demonstrated to be more effective than exenatide twice a day, by 1.51% vs.0.99% [94]

Pivoting back to the obesity space, a year-long Phase 2 study comparing semaglutide daily to 0.6 mg of liraglutide daily and placebo demonstrated the superiority of semaglutide over liraglutide in all doses above 0.2 mg (NCT02453711)

In this issue of the JCI , Farokhnia and colleagues used a reverse translational approach to examine the effects of enhancing GLP-1R activity either through synthetic agonists or inhibition of its degrading enzyme, dipeptidyl peptidase-4 (DPP-4) on alcohol consumption in both humans and preclinical models (Figure 1) (4)