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Whole brain microscopy following the injection of fluorescently labeled semaglutide revealed that semaglutide is present in parts of the hypothalamus, including the DMH, ARC, PVH, medial mamillary nucleus, and SON [59]

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While numerous studies have shown the benefits of semaglutide, we often see similar outcomes when patients achieve a healthy weight through other means, such as surgery. Further research into semaglutide and other hormone agonist medications is needed to determine which effects are independent of weight loss, advised Ali