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By interacting with parts of the brain that reduce appetite and signal fullness, semaglutide effectively controls hunger and supports weight loss efforts

The difference becomes more pronounced with higher-dose injectable semaglutide: Wegovy (2.4 mg weekly) demonstrated mean weight loss of approximately 15% of body weight in the STEP clinical trial program for obesity management, substantially exceeding outcomes typically seen with oral semaglutide at diabetes-approved doses
