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Amino acid substitutions : Specific amino acids within the peptide backbone are reported to have been substituted or modified to improve resistance to enzymatic degradation, including by dipeptidyl peptidase-4 (DPP-4), thereby improving metabolic stability

Additionally, the liquid formulation can be easier to dose in pediatric patients, who may require smaller, more precise doses based on their weight

Some of these drugs may influence the bodys sugar and fat metabolism or the function of organs such as the liver