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Methods Based on a systematic literature review (SLR) and Bayesian network meta-analysis (NMA), the efficacy and safety of semaglutide 2.4 mg, liraglutide 3 mg and tirzepatide 5, 10 and 15 mg were compared in adults without type 2 diabetes, and with either obesity (body mass index [BMI]30 kg/m2) or overweight (BMI27 kg/m2) with 1 obesity-related complication

You lose weight when you burn more calories than you take in.

Diabetic ketoacidosis (DKA) presents a severe complication of diabetes mellitus (DM), characterized by elevated blood sugar levels, metabolic acidosis, and ketosis

Given the heterogeneity of the included evidencespanning case reports, pharmacovigilance analyses, and observational cohortsthis review is framed primarily as a signal-detection and evidence-mapping exercise rather than a causal-inference analysis