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Sites of protease/peptidase vulnerabilities in GLP-1 were removed by amino acid substitution and the peptide backbone was bis-lipidated to promote MEDI7219 reversible plasma protein binding without affecting potency

Postpartum mothers and their healthcare providers often face the challenge of limited data regarding the safety of drug therapies during lactation

Considerations regarding adverse effects and contraindications for different drug classes are provided to help guide treatment decision-making when considering pharmacotherapy for weight management in patients with obesity.

Then, we will discuss the approaches that can increase the endogenous production of GLP-1 through various stimuli