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This corresponded to a 0.34 mmHg reduction in systolic blood pressure for every 1% of weight loss
Together, these results suggest that enhanced alpha-cell GLP-1 production may be an early response to metabolic dysregulation, suggesting that the adaptation to metabolic stress involves a greater reliance on this intra-islet paracrine signaling for glucose homeostasis
Further details regarding the characteristics of the included studies can be found in Tables 12
Plan sponsors should take a comprehensive approach to managing obesity that includes both a pharmacy benefit and medical benefit perspective
