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Bax: Bcl-2-associated x

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Older adults over age sixty-five may experience different side effect profiles and weight loss patterns than younger users

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Innovative designs incorporating active comparators, adaptive frameworks, and biomarker-driven endpoints (e.g., CSF/serum NfL, p-tau, microglial PET, synaptic markers) will be critical to generate interpretable efficacy signals

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Type 2 diabetes is a progressive condition requiring ongoing management, though some patients may reduce therapy with sustained lifestyle modifications under medical supervision

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