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Self-pay pricing agreements and the emergence of oral GLP-1 medications are expected to expand access for individuals.

Tirzepatide for Obesity Treatment and Diabetes Prevention "3y treatment with tirzepatide in persons with obesity and prediabetes resulted in substantial and sustained weight reduction and a lower risk (HR: 0.12) of progression to type 2 DM" @NEJM

Have not responded adequately to diet and lifestyle interventions alone
