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The newly added factors were high LDL cholesterol and untreated vision loss
It remains unclear, however, whether such effects mitigate hypoxia risk and ultimately fibrosis and nephron loss as described below
Furthermore, the possible promotion of cancer cell growth is increasingly being discussed with contradictory results (Table 4) that require clarification
PIO was the first antihyperglycemic medication that demonstrated beneficial liver effects in a small RCT, which analyzed data from 55 individuals with prediabetes/diabetes and biopsy-proven NASH [48]
