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What clinical trials show (or dont show) Across randomized trials and pooled safety data: acne is not consistently reported as a side effect it wasnt even a predefined outcome in most studies And in large meta-analyses: theres no clear increase in acne incidence linked to GLP-1 medications Thats important

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Exercise recommendations for weight maintenance are more intensive than those for general health

Interventions that support mitochondrial efficiency, stabilize nutrient sensing, and limit the accumulation of senescent cells may contribute to preserving physiological resilience, even if they do not directly alter the primary drivers of aging