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Gilmartin J

About the Study In the present study, researchers examined the associations between genetically predicted GLP-1R activation and mental health outcomes

GLP-1 receptor agonists appear to shift immune activity from inflammatory to regulatory without compromising protective immunity

Mast cells are now thought to also play a pathogenic role in the condition.[ref] Researchers have found that the average prostaglandin D2 levels (an indicator of mast cell activation) are higher in people with rheumatoid arthritis than in healthy controls.[ref] Related article : Rheumatoid arthritis genes Mast cells may play a role in obesity and diabetes: It has been known for a while that obesity is linked to increased systemic inflammation