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Mounjaro (tirzepatide) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist licensed in the UK for the treatment of type 2 diabetes mellitus

It was FDA approved in 2023 and has shown impressive results so far

Mechanism of Action: Tirzepatide vs Exendin-4-Based GLP-1 Agonists Understanding the mechanistic differences between tirzepatide and exendin-4-based therapies is essential for appreciating their distinct clinical profiles

The mechanism of action involves dual agonism at both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors