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The evidence comes from the OASIS 4 clinical trial, which followed adults with overweight or obesity for 71 weeks

Starting doses are usually 300 mg daily, gradually increased
Semaglutide is the active ingredient in Novo Nordisks best-selling GLP-1 therapies Wegovy (weight loss) and Ozempic (Type 2 diabetes), and the upcoming patent expiry is expected to open the door for multiple Indian drugmakers to enter the fast-growing market with lower-cost alternatives

A smaller proportion of patients with proliferative DR indicated that SGLT2i may ameliorate development of advanced DR
