semaglutide addiction clinical trials Once-weekly versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trial semaglutide alcohol use disorder study
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While both target weight loss through different mechanisms, dual therapy carries cardiovascular and metabolic risks that demand provider oversight and individual assessment before proceeding
This is why anyone considering, using or prescribing GLP-1 medication should pair it with: Progressive resistance training (Jensen 2024) High-quality protein at each meal (Phillips & Paddon-Jones 2023) Lower-glycaemic, minimally processed foods (Ludwig & Ebbeling 2022) Adequate sleep and stress management (Walker 2020) These behaviours protect muscle, bone, metabolic rate and long-term health things the medication cannot do on its own

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