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1, \(f\) represents concentration, \(t\) represents time, \(e\) is the base of natural logarithms, \(Y0\) is the initial concentration of post-injection, \(Y1\) is the final concentration, and \(k\) is the rate constant, expressed in inverse minutes
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Una vez que el GLP-1 alcanza la circulacin, tiene una vida media de solo dos minutos, debido a la rpida degradacin por parte de la dipeptidil peptidasa-4
The STEP-1 trial is considered the pivotal trial that demonstrated 14.9% weight loss at 68 weeks with semaglutide 2.4 mg [142]
