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Although causal incremental benefit cannot be established because of the single-arm design without a 0.5-mg maintenance comparator, these findings may support clinical decision-making regarding dose intensification in patients experiencing suboptimal control with 0.5-mg semaglutide

Interestingly, GLP-1 is a hormone naturally produced in the gut after a meal

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Retatrutide is the first triple-agonist peptide targeting GLP-1, GIP, and glucagon receptors simultaneously
