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Visiongain Insight: Competition in next-generation obesity therapies will increasingly depend on efficacy, preservation of lean mass, cardiovascular outcomes and dosing convenience

Actually, SAT is very important, rendering any incapacity to engage new adipose cells to store excess lipids in the SAT as a preamble to the hypertrophic (unhealthy) growth of WAT, which is further characterized by an accrual infiltration of macrophages, extensive fibrosis, limited angiogenesis and ongoing hypoxia [63]

This is consistent with research suggesting that these drugs broadly reduce neuroinflammation, which may also be a mechanism through which they improve anxiety and depression and reduce suicidality

CMS is evaluating Medicare coverage expansion to cardiovascular prevention, projected to add USD 12.4 billion to the annual U.S