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Groundbreaking Clinical Trial Reveals Lubiprostone, a Constipation Medication, Enhances Kidney Function Sep 22, 2025 Groundbreaking Clinical Trial Reveals Lubiprostone, a Constipation Medication, Enhances Kidney Function Whats CKD & the Problem

GLP-1 supports mental wellness by restoring microbial balance and improving satiety signalling, potentially reducing emotional eating and cravings (Singh et al, 2024)

Beyond hormonal changes, several interconnected factors may contribute to perimenopausal weight gain: Metabolic slowdown : Basal metabolic rate naturally decreases with age, meaning the body burns fewer calories at rest Muscle mass loss : Sarcopenia (age-related muscle loss) accelerates during perimenopause, further reducing metabolic rate Sleep disruption : Night sweats and insomnia, common perimenopausal symptoms, interfere with hormones regulating appetite and glucose metabolism Mood changes : Anxiety, depression, and stress during this transition may lead to emotional eating patterns Reduced physical activity : Fatigue, joint pain, and other symptoms may decrease exercise tolerance Research suggests women may gain weight gradually during perimenopause, though individual experiences vary considerably