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examined long- and short-term CR in femora and vertebrae, demonstrating that the initially deleterious impact of CR on cancellous bone diminishes with age

These medications can be expensive, and insurance coverage for weight loss varies widely

When administered subcutaneously once a week, semaglutide significantly and meaningfully reduces weight, along with lifestyle interventions such as increased physical activity and reduced calorie intake

The ideal candidate is someone who has a meaningful fat-loss goal, defined as 20 lbs or more to reduce, who is also concerned about how skin quality and connective tissue integrity will hold up through that process