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It enhances glucose-dependent insulin secretion, suppresses inappropriate glucagon release, and slows gastric emptying

These include potential future price changes, innovations that could improve long-term adherence, and the possibility that scientific understanding of treatment duration may evolve

Thus, one could doubt that deceleration of the typical course of postprandial gastric emptying is what explains retained gastric contents

Model Predictions Because of substantial log-normal within-individual variability, standard computation of reference subject simulations, as well as population predictions and weighted residuals reported by the nonlinear mixed-effects modelling software (NONMEM) are poor measures to reflect data