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Description
doi: 10.1002/acr2.70103
The term solubility in the BCS report refers to the therapeutic dose of a drug that is soluble in an aqueous media which has pre-specified characteristics (volume, pH and temperature)

Adipose tissue, particularly visceral fat, is metabolically active and produces pro-inflammatory cytokines including TNF-alpha, IL-6, and leptin

Visceral fatthe metabolically active adipose tissue surrounding internal organsposes greater health risks than subcutaneous fat, driving insulin resistance, cardiovascular disease, and metabolic dysfunction