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Researchers are also investigating whether the effects differ based on baseline drinking severity, metabolic status, and genetic factors related to GLP-1 receptor expression and function

The good news is that GLP-1 constipation is usually manageable

Multiple NIH institutes, including NIAAA and NIDA, have invested tens of millions in clinical trials studying GLP-1 receptor agonists for substance use disorders, including alcohol addiction

In fact, hair loss rates after bariatric surgery are often higher than those seen with GLP-1 therapy, with some studies reporting rates of 30-40% in the first year post-surgery