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The net effect varies considerably between individuals depending on their baseline gut motility, diet, hydration, and dose
doi: 10.1016/j.cmet.2019.01.003 171 GoldenGJWuVHHamiltonJTAmsesKRShapiroMRSada JappAet al
Science (2006) 313(5790):113740.10.1126/science.1128294 138 OtaTGayetCGinsbergHN
Hormonal fluctuations are another key consideration: Rapid weight loss can significantly alter SHBG and free testosterone levels, potentially leading to symptoms of androgen excess or deficiency even when the prescribed testosterone dose remains unchanged
