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"When clinically appropriate, the clinician may pair these interventions with medications, subject to their availability," the company said in a statement.

More serious potential side effects include: Gallbladder issues Pancreatitis Potential risk for heightened thyroid c-cell tumors Kidney injury Tirzepatide vs Semaglutide cost for weight loss Securing insurance coverage for weight loss medications can be challenging, so the cost will often come completely out-of-pocket

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Across the entire trial (week 0 to 88) for the TRE, significantly more patients in the tirzepatide group achieved a body weight loss of 5% (97.3% vs 70.3% for the placebo