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For pregnancy planning, discontinuation timing is product-specific: Semaglutide (Ozempic, Wegovy): Stop at least 2 months before attempting conception For other GLP-1 medications: Consult the specific product information and discuss with your healthcare provider Healthcare professionals should counsel patients of reproductive age about these considerations and the importance of effective contraception whilst on treatment

Studies are currently examining the role of GLP-1s in conditions such as heart failure with preserved ejection fraction, metabolic dysfunction-associated steatohepatitis, Alzheimers disease, Parkinsons disease, peripheral artery disease, diabetic kidney disease and cancer, and other pharmaceutical manufacturers are expected to apply for similar GLP-1 label expansions in the future

Avoiding trigger foodssuch as spicy dishes, citrus, chocolate, caffeine, and fatty foodshelps many patients feel more comfortable on semaglutide

It is currently the focus of ongoing non-clinical and preclinical studies that aim to better understand its role in metabolic signaling