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The full effects become more evident once the higher doses are introduced, so weight loss may speed up after the first month or two of treatment

and selected members of the Ruminococcaceae family, have similarly been associated with pro-inflammatory or dysmetabolic states, although their role in modulating GLP-1 RA efficacy remains speculative

In addition, injectable semaglutide has greater weight reduction than oral semaglutide [73]
