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Personalized Dosing and Titration We start at the lowest effective dose and adjust gradually based on your response, side effects, and lab results
Glucagon like peptide-1 accelerates colonic transit via central CRF and peripheral vagal pathways in conscious rats
Figure 27: Photograph of Sir James Black (1924-2010), credit: Lyall

This work demonstrated that GLP-1RA treatment was associated with a significant 29% reduction in MALOs compared to non-use (IRR: 0.71, 95%CI: 0.57-0.88, P = 0.003) over a median follow-up of approximately 70,045 patient-years
