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Description
CagriSema: Fixed-dose combination of cagrilintide (amylin analog) and semaglutide (GLP-1 agonist)
In the STEP 1 trial with 1,961 participants, patients taking 2.4 mg semaglutide weekly alongside reduced caloric intake and increased physical activity lost an average of 14.9% of their body weight over 68 weeks
Without insulin, ketogenesis is uninhibited, resulting in the characteristic DKA risk
[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Shaman A.M., Bain S.C., Bakris G.L., Buse J.B., Idorn T., Mahaffey K.W., Mann J.F.E., Nauck M.A., Rasmussen S., Rossing P., et al
