glp 1 microdose reddit A new analysis—using AI to analyze thousands of posts—suggests some people may be experiencing lesser-known effects not formally listed on the labels of these weight loss drugs. 📸 Getty/gpointstudio Is Microdosing GLP-1s Safe? What
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LDL cholesterol decreases by 3-7%, total cholesterol reduces by 3-8%, and HDL cholesterol modestly increases by 2-5%, with additional reductions in non-HDL cholesterol of 5-10%

**GLORY-1 Phase 3 Study** The GLORY-1 study, the first phase 3 study worldwide to examine a GLP-1R/GCGR dual agonist for weight loss, showed impressive results
In the STEP trials, semaglutide 2.4mg weekly resulted in mean weight reductions of 1517% over 68 weeks, whilst tirzepatide in the SURPASS trials showed reductions of 1520% (Kushner et al