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The theoretical difference is that a liquid held under the tongue maintains more uniform contact with the absorptive tissue than a dissolving tablet, which may distribute unevenly across the oral cavity

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Zepbound (tirzepatide) for Weight Management : Approved in November 2023 for chronic weight management in adults with a body mass index (BMI) of 30 kg/m or greater (obesity), or 27 kg/m or greater (overweight) with at least one weight-related comorbidity such as hypertension, type 2 diabetes, or dyslipidemia