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Phase 2 results (48 weeks, published in NEJM) The landmark Phase 2 trial randomized 338 participants across multiple dose groups

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Regulatory Guidelines for ADA Assessment The assessment of immunogenicity is a key part of the regulatory approval process for biologics

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This phenomenon suggests that although semaglutide offers significant protection against neurovascular and metabolic changes, the maintenance of adverse dietary stimuli may compromise the effectiveness of semaglutide in restoring microglial homeostasis

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