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Because obesity can drive chronic inflammation, raise insulin levels, and alter the metabolic environment around tumors, researchers are now asking whether GLP-1 drugs may help change those conditions in ways that could affect cancer risk or outcomes, not just body weight

Glucagon-like peptide-1/glucagon receptor agonism associates with reduced metabolic adaptation and higher fat oxidation: a randomized trial

Empagliflozin in patients with chronic kidney disease

The rodent findings may not directly translate to human risk due to significant species differences in thyroid C-cell biology and GLP-1 receptor expression
