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A comprehensive literature search was conducted across the PubMed, Embase, and Google Scholar databases for peer-reviewed articles published from inception through June 15, 2026, focusing on the landmark SURPASS, SURMOUNT, and SUMMIT trial programs, relevant cardiorenal post hoc analyses, emerging body recomposition trials, and real-world cohort-switching protocols

A new secret shopper study published in JAMA has raised concerns about the oversight of online vendors prescribing glucagon-like peptide-1 receptor agonists (GLP-1 RAs), the popular class of

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